Gelatin is made from animal skins, bones, and tendons through a series of complex physical and chemical treatments. It is fat-free, high in protein, and easily absorbed by the body, with physical properties such as high viscosity, strong gelling power, and ready gel formation. Pharmaceutical gelatin should be dry, clean, uniform, and free of impurities. It appears as fine, pale yellow to yellow granules, should pass through a standard sieve with a 4mm aperture, and its solution should be free of odor.

Gelatin of this kind has long been known as medical gelatin, or pharmaceutical gelatin. It is mainly used in plasma substitutes, hemostatic sponges, soft and hard capsules, tablet sugar-coating materials, encapsulation materials for microspheres and microcapsules, and other sustained-release and biofilm materials. Succinylated gelatin for injection is prepared by spray-drying and freeze-drying processes and made into solid preparations, which improves its stability, makes transport and storage easier, and overcomes the instability and inconvenient transport and storage of peptide-based biological infusion products.

It should be noted that most gelatin and collagen on the market is extracted from the connective and hard aggregate tissues of pigs and cattle, which in turn limits its use. A considerable number of people around the world cannot consume pork products, such as Jewish and Muslim consumers and vegetarians, and since gelatin products often do not indicate their animal origin, their use of gelatin is limited.
At the same time, their hydrophilic and immunologically compatible characteristics give them new biomedical properties, making them a research focus in recent years. The application and study of gelatin derivatives and their compounds have likewise attracted growing attention. A 20% lidocaine gelatin fiber mesh not only provides better hemostasis than oxidized cellulose and gelatin sponges, but also offers sustained-release analgesia.

Soft capsules, also known as softgels, are single-layer, highly sealed capsules. The capsule shell is made of gelatin and other raw materials in varying proportions, and is both elastic and soft. Pigments and light-protective agents are selected mainly according to customer requirements and product characteristics.
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